Laboratory Members
Charles Sagerström, Ph.D.
PROFESSOR
DEPARTMENT OF PEDIATRICS
Postdoctoral Fellow
Whitehead Institute/MIT
1993-1997
Ph.D., Immunology
Stanford University
1993
B.A., Biology
Macalester College
1987
PROFESSOR
DEPARTMENT OF PEDIATRICS
Postdoctoral Fellow
Whitehead Institute/MIT
1993-1997
Ph.D., Immunology
Stanford University
1993
B.A., Biology
Macalester College
1987
My research career started in college with an interest in Immunology that I pursued through graduate school. I was particularly interested in cell fate decisions among immune cells and this led me to carry out postdoctoral research studying embryonic development. I started my own research group at the University of Massachusetts Medical School in 1997, and in 2019 I relocated to the University of Colorado Medical School. My group has a long-standing interest in understanding how embryonic development is programmed at the level of gene expression. We primarily use zebrafish as a model organism and we apply genome-wide approaches to study transcriptional regulation in early embryogenesis.
Yong-ll Kim, Ph.D. instructor Ph.D., Microbiology Wonkwang University School of Medicine 2017 M.S., Biology Chungnam National University 2011 B.S., Biology Chungnam National University 2009 When I was an undergraduate student, I worked with a master’s degree student who was trying to generate a mutant line of zebrafish using insertional mutagenesis. After joining my master’s degree program, I worked on a project to characterize cells that form bone. I generated a bone-specific col10a1:GFP transgenic zebrafish. I joined my Ph.D. program and started working on my project that focused on the role of peroxisome-related genes during zebrafish development. During this time, I generated several alleles of zebrafish mutants and transgenic zebrafish related to peroxisome biology. Currently I work in the Sagerström lab as a postdoctoral research fellow. Here, my research focuses on investigating the role of hindbrain-related genes during zebrafish development. |
Austin Adkins, Ph.D. postdoctoral fellow Ph.D., Biomedical Sciences Research, Neuroscience Eastern Virginia Medical School 2023 M.S., Biomedical Sciences Research, Neuroscience Eastern Virginia Medical School 2020 B.A., Marine Biology Old Dominion University 2017 During my time at Eastern Virginia Medical School, my research focused on the mechanisms by which the sleep and neuroimmune systems are linked and integrated during the stress response, how these interactions may change based on circuit manipulations, how these alterations may modulate other systems (e.g., learning and memory, behaviors, sensorimotor function, etc.), and their relevance for psychiatric diseases/disorders. I joined the Sagerström lab in the fall of 2023. My current project is attempting to elucidate the role of the early transcription factors Meis and Prep in hindbrain development; especially during the transition from maternal to zygotic stages. These factors are uniquely interesting as they are critical in the hindbrain during early development, but also play key roles in sleep, immunity, and learning and memory in adulthood. In the future, I hope to define the link between alterations or mutations in Prep/Meis that may lead to neurodevelopmental disorders, and how they may be associated to these individuals’ predisposition for sleep and immune system comorbidities, and increased susceptibility for anxiety-related disorders and neurodegenerative diseases later in life. |
Sylvia Nunez Ph.D. CANDIDATE B.S., Integrative Biology University of Illinois at Urbana-Champaign 2016 During my undergraduate career at the University of Illinois at Urbana-Champaign, I had the opportunity to work in Dr. Felipe Soto-Adames's lab studying the molecular evolution of paralogous genes involved in muscle contractions in insects and decapods. I joined the Sagerström lab as a PhD student in Cell Biology, Stem Cells, and Development researching cell fate decisions at the midbrain-hindbrain boundary in zebrafish. |
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Cameron Bennett ph.d. candidate B.S., Genomics and Molecular Genetics Michigan State University 2021 While an undergraduate at Michigan State University, I had the opportunity to work in Dr. Ingo Braasch’s lab. My research focused on the functional analysis of the endothelin gene Edn4 in neural crest cells and their derivatives in zebrafish. I joined the Sagerström lab as a Ph.D. student in the Molecular Biology program in 2022, and my research focuses on investigating the role of Vgll3 in the transcriptional regulation of early embryonic hindbrain cell fate pathways. |
Katie Glowinski professional research assistant B.S., Biology Concordia University St. Paul 2021 In my undergrad at Concordia, I had the opportunity to work under and learn from Dr. Mandy Brosnahan and Dr. Taylor Mach in a study focused on S. aureus. My individual research investigated if carrier rates were impacted by travel outside of the United States. In my second year in the study, the research focused on gene screening in confirmed methicillin resistant samples. After graduation, I began working in a Quality Control lab at Bio-Techne in Minneapolis, where my lab's role was to ensure our protein and antibody products were meeting qualifications before being shipped out for use. I recently moved out to Colorado, and joined the Sagerstrom lab in September 2023. I am excited to be on this team and learn more from the great people around me! |
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Lab Alumni Heather Reichenbach, B.A. (2023) Clinical Research Coordinator | UCD Anschutz Medical Campus, Aurora, CO Ethan Wright, M.Sc. (2023) Research Lab Supervisor | Boston Children's Hospital, Harvard Medical School; Boston, MA Jelena Kresoja-Rakic, Ph.D. (2023) Scientist | ArtisanBio; Louisville, CO Jessica Warns, Ph.D. (2022) Adjunct Professor | Northern State University; Aberdeen, SD |
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