SAGERSTRÖM LAB
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PEOPLE

Principal Investigator 

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Charles Sagerström, PhD
Professor,
Department of Pediatrics.
 

B.A., Biology
 Macalester College 
1987
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PhD Immunology
 Stanford University
1993

Postdoctoral Fellow
Whitehead Institute/MIT
1993-1997


​My research career started in college with an interest in Immunology that I pursued through graduate school. I was particularly interested in cell fate decisions among immune cells and this led me to carry out postdoctoral research studying embryonic development. I started my own research group at the University of Massachusetts Medical School in 1997 and in 2019 I relocated to the University of Colorado Medical School. My group has a long-standing interest in understanding how embryonic development is programmed at the level of gene expression. We primarily use zebrafish as a model organism and we apply genome-wide approaches to study transcriptional regulation in early embryogenesis.

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We are always interested in having qualified individuals join our lab! 

​Currently, we have postdoctoral openings available through the Section of Developmental Biology Postdoctoral Training Program. Click here for additional details.
Email Charles

Current Lab Members 

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Jessica Warns, PhD
post doctoral fellow
B.S. Molecular Biology
Muskingum University
2013
 
PhD Biochemistry and Molecular Biology
University of North Dakota
2018

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During my undergraduate studies, I had the opportunity to perform research on optimizing the detection of a transcript involved in Chronic Myeloid Leukemia known as BCL-ABL. During this time, I fell in love with research and decided to attend the University of North Dakota for graduate school. While I had several different projects, my thesis work involved investigating the role of a cholesterol metabolite in colon cancer, specifically 27-hydroxycholesterol on colon cancer cell proliferation and AKT signaling under my advisor Dr. Othman Ghribi. After I graduated with my PhD in 2018, I took a position at Fort Lewis College in Durango, CO as a visiting instructor of Biochemistry. After completing teaching, I began to work in the Charles Sagerstrӧm Lab as a postdoctoral fellow in 2019. My project involves studying the role of a transcription factor NF-Y in regulation of cilia genes and ciliogenesis.
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Yong-ll Kim, PhD​
POst doctoral Fellow
B.S., Biology
Chungnam National University
2009


M.S., Biology 
Chungnam National University
2011


PhD., Microbiology       Wonkwang University School of Medicine
​2017 


When I undergraduate student, I was working with a master’s degree student who was trying to generate a mutant line of zebrafish using insertional mutagenesis.
After joining the Master’s degree program, I worked on a project to characterize cells that form bone. I generated a bone-specific col10a1
:GFP transgenic zebrafish.
I joined Ph.D. program and started working on my project that focused on the role of peroxisome-related genes during zebrafish development. During this time, I generated several alleles of zebrafish mutants and transgenic zebrafish related to peroxisome biology.
​Now, I'm working in the Sagerstrom lab as a postdoctoral research fellow. Here, my research focuses on investiging the role of hindbrain related genes during zebrafish development.
EMAIL YONG-IL
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Ethan Wright, MSc
PROFESSIONAL RESEARCH ASSISTANT 
B.S. Genetics
University of Georgia
2016 

MSc. Molecular Biology University of Colorado
​2019
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My research interest is in transcriptional regulation during early neurogenesis. 

While at The University of Georgia, I performed my undergraduate research in Jonathan Eggenschwiler's lab. My project focused on Sonic Hedgehog signaling in mouse neural tube closure.

My graduate research was performed in Eugenia Killian's lab. My work focused on the alternative splicing factor, Caper, and its role in Drosophila neuron development. 

I joined the Sagerström lab in the summer of 2019. My current project focuses on  the early transcription factors Meis and Prep. The primary focus of the project is to understand the role of these factors in hindbrain development; especially  during the transition from maternal to zygotic stages. These factors are uniquely  interesting as they are critical in the hindbrain during early development but then also play a key role in cancer during adulthood. 
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